Yeah the blistering fast and bloody play of LOS was a big draw for me. I'd not want to slow it. There's a lot of internet fandom and chatter focusing on very fast-playing rules; see Song of Blades and Heroes, or the dozen variants of FUBAR. Whether this translates into retail success I have no clue.
My thought is that it was often said, back in th' day, LOS had a problem with scale; you couldn't go up much from a fiend without things breaking.
So I wonder if, with a bigger die, you might be able to expand the range of figures that can feasibly be played. Thus easing the transition from straight LOS to tabletop skirmish with regular infantry and vehicles? Deadzone doesn't try to get above the size of LOS heavy powered infantry and light vehicles. Theoretically it's a taster for a later, full-sized skirmish game, and they're using the Deadzone KS to stir up some chatter and get people to buy in, and to get their core troops in plastic from the get-go. Nevertheless it might be informative that they started at the 1-2 squads end of the spectrum.
Personally I think (imagine, really, I'm no industry insider) there's a fair market for skirmish sized games. Warmachine, Hordes, Deadzone, etc. So I'd be excited to see LOS much as it was, then a tabletop version for small tables with a lot of terrain; representing urban environments, industrial compounds, and freakin' big underground or shipboard actions. This is more "in range" of original LOS than a "full sized" two platoons and some armour game per modern 40K.
All of which is possibly of interest when deciding how much up-scalablity you want to biuld into the core LOS mechanics. And if you decide you want to be able to scale up, then I would be in favour of keeping the "one roll, one kill" lethality, even honing it a bit, and going with a bigger die.